WHOLE GENOME SEQUENCING ANALYSIS OF MYCOBACTERIUM TUBERCULOSIS REVEALS CIRCULATING STRAIN TYPES AND DRUG-RESISTANCE MUTATIONS IN THE PHILIPPINES

Whole genome sequencing analysis of Mycobacterium tuberculosis reveals circulating strain types and drug-resistance mutations in the Philippines

Abstract The Philippines is a high-incidence country for tuberculosis, with the increasing prevalence of multi- (MDR-TB) and extensively-drug (XDR-TB) resistant Mycobacterium tuberculosis strains posing difficulties to disease control.Understanding the genetic diversity of circulating strains can provide insights into underlying drug resistance mut

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Modeling the link beam behavior to evaluate its performance according to FEMA 356 and calculating the target displacement of performance levels

The presence of the link beam in eccentrically braced frames is primarily responsible for different behavior of this frame with other structural systems.In accordance with the FEMA 356, for the evaluation of the performance of the link beam in all of its behavioral areas, the plastic rotation of the plastic hinges is required.In many studies, for t

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